https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Circulating RNA differences between patients with stable and progressive idiopathic pulmonary fibrosis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38777 Tue 08 Feb 2022 12:17:52 AEDT ]]> Gastroesophageal reflux and antacid therapy in IPF: Analysis from the Australia IPF Registry https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46902 8. Overall, there was no difference in survival or disease progression, regardless of antacid treatment, GORD diagnosis or GORD symptoms. Conclusions: Neither the use of antacid therapy nor the presence of GORD symptoms affects longer term outcomes in IPF patients. This contributes to the increasing evidence that antacid therapy may not be beneficial in IPF patients and that GORD directed therapy should be considered on an individual basis to treat the symptoms of reflux.]]> Tue 06 Dec 2022 16:07:24 AEDT ]]> Limited (information only) patient education programs for adults with asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8458 Sat 24 Mar 2018 08:38:58 AEDT ]]> Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7912 Sat 24 Mar 2018 08:37:40 AEDT ]]> Fully integrating pathophysiological insights in COPD: an updated working disease model to broaden therapeutic vision https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38890 Fri 25 Feb 2022 17:03:28 AEDT ]]> Hypoxia-inducible factor and bacterial infections in chronic obstructive pulmonary disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40012 Streptococcus pneumoniae, Haemophilus influenzae and Pseudomonas aeruginosa)to induce infection in both the respiratory and gastroin-testinal (GI) tracts. However, the importance and mechanism of HIF-1αin augmenting PAFR-dependent bacterial infections in COPD are poorly understood. Here, we review the evidence for the roles of local tissue hypoxia-induced inflammation, HIF-1α and PAFR in facilitating bacterial infections in COPD. Blocking PAFR may provide a novel antimicrobial approach to manage bacterial infections in COPD.]]> Fri 22 Jul 2022 13:06:35 AEST ]]>